STANDARDIZATION OF ANTIMENINGOCOCCIC SERUM
نویسندگان
چکیده
منابع مشابه
Standardization of Antimeningococcic Serum
Experiments were made for the purpose of testing the reaction of protection against infection as a measure of potency of antimeningococcic serum. The results of the experiments were extremely variable and bore no relation to the quality of the sera as determined by the period of immunization of the horses from which they were obtained, or the indications of efficiency based upon their employmen...
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In an attempt to simplify the manufacture of an efficacious antimeningococcus serum an experimental study has been made of a number of sera produced with a few or with single strains of meningococcus, the therapeutic polyvalent serum produced at The Rockefeller Institute with more than 50 strains being used as a standard of comparison. It was found that horses injected with an antigen limited t...
متن کاملSimplified Production of Antimeningococcic
Although a large amount of work in several countries has been done relative to the production of an effective antimeningococcic serum, the problems involved have not yet been wholly resolved. The increased demands arising from war conditions acted as a potent stimulus first to simplify manufacture and then to insure an effective product. This paper records primarily attempts to simplify the man...
متن کاملStandardization of serum fructosamine assays.
We have calibrated a secondary serum protein standard by use (as primary standards) of samples of albumin and polylysine glycated with [14C]glucose in vitro, the glycation of which was assessed by radioactivity measurements and by elementary analysis for C and N. Using this standard for calibration in our improved fructosamine assay, one obtains an average fructosamine value of 247 mumol/L for ...
متن کاملStandardization of the Antimeningitis Serum
The high variability in infectivity of Diplococcus intracellularis makes it impracticable to standardize the antimeningitis serum on the basis of the virulence of the diplococcus. The irregularity of reaction of small animals to the poison or endotoxin of Diplococcus intracellularis makes it impracticable to standardize the antimeningitis serum on the basis of endotoxic value. The want of unifo...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1918
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.28.6.779